THE FETTE COMPACTING EFFICIENCY GUIDE
The Fette Compacting Efficiency Guide is the guidance System for our entire product and service range.
Merck in China
TARGET: TEN BILLIONS
Merck’s second largest pharmaceutical production site is currently taking shape on the east coast of China, just around a two-hour drive away from Shanghai. When the factory reaches full capacity in 2021, plans call for the production of ten billion tablets a year in Nantong. The tablet presses required to achieve this come from Fette Compacting.
PHARMAMARKT 2020: UPSWING TURN FOR GLOBAL PRODUCTION
According to current studies, pharmaceutical producers can look forward to growing demand in the years to come. Growth means that more people receive access to medical care on the one hand while special medication for rare diseases gains in importance on the other. This increases international requirements on flexibility and quality in production.
Machine technology is obliged to offer the right solutions for each product and each requirement – increasingly in accordance with uniform global standards. In an interview, Rainer Krugmann, Global Director Sales at Fette Compacting, provides an outlook as to what trends Fette Compacting can anticipate in the production of solid formulations.
CONTINUOUS MANUFACTURING: MONTHS BECOME HOURS
Product approval in real time? Producers of pharmaceuticals and machine manufacturers worldwide are working on this vision. Thanks to Continuous Manufacturing (CM), delays attributable to separate production processes, complex conversions and long offline analyses could soon be a thing of the past. Pilot plants are already available but it’s still early days for technology in the area of commercial pharmaceutical production. In an interview, Dr. Martin Schöler from Fette Compacting outlines the discoveries made by these pilot projects and how the CM vision is to become a reality.
A PRODUCT WITHIN A PRODUCT: CROSS-CONTAMINATION AS A CHALLENGE FOR TABLETING
Pharmaceutical production increasingly involves the use of highly-active ingredients. This is also accompanied by increased demands on containment. Cross-contamination in particular becomes a risk for patient safety and product quality. But what requirements actually apply here and what technologies offer effective protection during tableting?
UNYIELDING IN THE FACE OF TOUGH INGREDIENTS
Pharmaceutical ingredients present tableting tools with tough challenges. Formulations containing minerals, for example, encourage wear. Thermolabile granulates tend to adhere, which presents a particular challenge to continuous production. Users can significantly reduce these effects and optimize the production process through the use of the right punch heads, materials and coatings.
LIT UP IN A FLASH: ACTIVE INGREDIENT ANALYSIS IN TABLETING
With medication, no matter the batch size, every single tablet must contain exactly the same amount of active ingredient in order to permit reliable administration to patients. Near-infrared spectroscopy (NIR) is a suitable inspection method for the material properties of pharmaceutical products. The VisioNIR LS system, from Fette Compacting and visiotec, offers an analytical method whose precision and speed is optimally matched to the requirements of tableting.
IN THE LAND OF INNOVATIONS: SUBSIDIARY OPENS IN SWITZERLAND
Switzerland is the international leader when it comes to innovation and exports in the pharmaceutical industry. With the aim of guaranteeing pharmaceutical companies even faster technical service on site, a subsidiary of Fette Compacting opened in Basel on May 1, 2015.
ANNIVERSARY: TEN YEARS IN NANJING
In October 2014 the LMT Group celebrated the tenth anniversary of its subsidiary Fette Compacting Nanjing. More than 250 guests and 120 staff accepted the invitation. On this occasion, managing director Olaf J. Müller gave the go-ahead for the LMT Group Academy China and informed the visitors about the company’s plans for a new building.
FROM THE WORLD OF GLOBAL CUSTOMER SUPPORT (PART 2): SEARCHING FOR CLUES
High-quality spare parts safeguard efficiency and process reliability over the entire life cycle of a plant. The qualitative differences which can arise between original and generic parts are shown by two scientific studies using compression rollers as an example.
TAKING GLOBAL RESPONSIBILITY – INTERPACK 2014 IN REVIEW
How can you make your production even more efficient while maintaining the very highest quality standards? At Interpack 2014, some 175,000 trade visitors from all over the world went in search of new approaches for the future of pharma and food production.