Highly-active substances demand particularly safe production processes. The use of Containment and WiP (Wash-in-Place) systems safeguards the health of operators. Product changeovers can be carried out significantly faster using WiP. Equipping a WiP machine with a Containment package permits entirely new possibilities when processing highly-active granulates.
Watch how optimal WiP and containment processes improve both productivity and safety.
Containment Guide – The manual describes the fundamentals and the framework conditions of a systematic measurement procedure and outlines the process for recording a tableting system`s relevant statuses. This system allows us to reliably determine a system`s retention capacity.
The author Dr.-Ing. Martin Schöler is Head of Engineering & Design at Fette Compacting GmbH. He is active member of the COP Containment D/A/CH and former member of the EHEDG Training and Education subgroup. After graduating from TU Dresden (Germany) he worked in Pune (India) and later joined the TU Dresden for his PhD on cleaning and hygienic design of processing machines. In 2011, he joined Fette Compacting GmbH.
Absolutely reliable containment is of increasing importance in the pharmaceutical production of Highly Potent Active Pharmaceutical Ingredients (HPAPI). The aim is to reliably protect patients from the risks of cross-contamination and to eliminate any risk for operators of the machine when handling highly-active substances. We developed the Containment Guard to meet these challenges while simultaneously safeguarding your efficiency during manufacturing. The system comprises:
Safety comes in seven cycles. All information about the test process
The measurement method is based on the SMEPAC Guideline. It is supplemented by the Containment Guard to include other practical aspects:
This makes it possible to achieve a reproducible evaluation specially for containment tableting systems.
Certificate based on the OEB level
Fette Compacting conducts this test in special test rooms in the customer center in Schwarzenbek. Successful testing is followed by the tablet presses receiving the Containment Guard certificate. The certificate levels are based on the OEB levels and/or the corresponding PDE values.
The exchangeable segment turret and efficient cleaning concept ensure high productivity on the part of the 1090i WIP. They permit fast product changeover and shorter downtimes. The 1090i WiP features a manual spray gun and a dust suction jet in the containment version. The Glatt flap system permits contamination-free material feed.
Extremely fast processes in production: the washable press room in the 2090i WiP ensures fast product changeover and shorter downtimes. The 2090i WiP features a manual spray gun and a dust suction jet in the containment version. The flap system permits contamination-free material feed.
During the production of large batches, the 3090i WiP double rotary tablet press ensures maximum productivity with little strain on operating personnel. With the aid of standard equipment such as automatic pre-washing, the 3090i WiP can be fully integrated in process automation. It is possible to swiftly change between products of varying shapes and sizes. Material is fed through a flap system in the containment version. The material container can be mounted and removed in an entirely contamination-free manner.
As a manufacturer, are you increasingly deploying highly-active substances? Then you can rely on the security offered by low-dust production. The optional containment package for the FE55 offers a highly-efficient standard platform.
The FE75 is the right choice when you make maximum demands on output without wanting to make any compromises in terms of safety.
The overview indicates the right Containment or WiP solution for your requirements.
Tablet output (max.)
|FE55 Containment||87||626,400||1,306 x 1,306 x 2,048||25 mm||approx. 3,800|
|FE75 Containment||115||1,656,000||1,463 x 1,463 x 2,046||25 mm||approx. 5,500|
|1090i WiP||30||216,000||960 x 960 x 2,034||25 mm||approx. 2,000|
|2090i WiP||45||324,000||1,220 x 1,220 x 2,022||25 mm||approx. 3,500|
|3090i WiP||75||1,080,000||1,390 x 1,390 x 2,024||25 mm||approx. 4,800|
Please do not hesitate to contact us if you have any queries. Together, we will develop ideas to make your production even more efficient, innovative and profitable.
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